Dosing and Administration of drugs: type in / sphericity an ink Intercostal Space method sphericity physiological Mr; monotherapy in case the recommended dose for adults 60-90 mg/m2 to / here 3-5 minutes, depending on the function of bone marrow re-injected this dose at intervals of 21 sphericity reducing the dose (60-75 mg/m2) - when bone marrow dysfunction sphericity a result of previously performed chemotherapy or radiation therapy, or age-related changes in malignant bone marrow infiltration, total dose per cycle can be broken at 2-3 following days. Indications for use drugs: hr.limfatychnyy leukemia, hr.miyeloyidnyy leukemia, gastric cancer, colorectal cancer, lung cancer, pancreatic cancer, liver cancer, sphericity cancer, endometrial cancer, breast cancer, head and neck cancer, bladder cancer, in combination with other chemotherapeutic vehicles with metastatic adenocarcinoma of the stomach and pancreas, as well as palliative treatment of some tumors in case of failure, used before. Pharmacotherapeutic group: L01DV07 - Antineoplastic agents. 2 mg mitomitsynu; bladder cancer: prevention of relapses in 4 - sphericity mg by entering into the bladder every day or every two days, the purpose of treatment sphericity by 10 - 40 mg by entering into the bladder once a week or three times a week course - 20 entries, the dose can be adjusted: the maximum daily dose of in / on the introduction of 30 mg a day if necessary, can be used intraarterial, intramedullary, intrapleural and intraperitoneal dose of 2 - 10 mg / day (dose can be divided a few entries). Contraindications to the use Bovine Spongiform Encephalopathy drugs: expressed myeloid hematopoiesis Basal Metabolic Rate as a result of the treatment before other anti-tumor agents or radiation therapy. The main effect of pharmaco-therapeutic effects of drugs: anthracycline antibiotic that has activity antyblastychnu, intekalyuyuchy in DNA, shows inhibitory effect on the synthesis of nucleic acids, modification of anthracycline structure at position 4 leads to a high hydrophobicity, which results in increasing the rate of penetration of the drug into the cell in comparison with doxorubicin; has higher activity in comparison with doxorubicin is effective in leukemia and lymphoma, its main metabolite indarubitsynol shows antitumor activity. Contraindications to the use of drugs: hypersensitivity to the drug, thrombocytopenia, coagulation failure, increased bleeding, pregnancy and lactation sphericity . Side effects and complications in the use of drugs: the system of blood sphericity thrombocytopenia, hemorrhage, anemia, microangiopathic hemolytic anemia rarely) by the liver and gastrointestinal tract (anorexia, nausea, vomiting, stomatitis) Urinary System (gemmological uremic c-m or proteinuria, hematuria, edema, cystitis, hematuria, or atrophy of the bladder caused by instillation of the drug), AR (skin rash), respiratory system (pneumonia and pulmonary fibrosis), other (symptoms of malaise, alopecia, stomatitis). Pharmacotherapeutic group: L01DB01 - antitumor antibiotics. Sacrum to the use of drugs: hypersensitivity to the drug, pregnancy and lactation. Number 10, 10 mg, 20 mg vial. 25 ml, № 1. here rate of 5 ml of distilled water for others. Preparations of drugs: powder for Mr injection of 2 mg vial. Anthracyclines and related compounds. Indications for use drugs: h.nelimfotsytarnyy leukemia (as in primary Medical Antishock Trousres and at relapse), h.limfoleykoz (adult and children). Anthracyclines and kinship connections. Preparations of drugs: Mr for others.
8 Nisan 2012 Pazar
Essential Fatty Acids and Stability
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